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KMID : 0363220200580100681
Korean Journal of Dermatology
2020 Volume.58 No. 10 p.681 ~ p.687
A Pilot Comparative Study of Alternating Blue and Red Light LED Phototherapy and Pulsed-dye Laser Therapy for Acne Vulgaris Treatment
Jeon Jae-Wook

Bae Joo-Youn
Jung Hye-Jung
Ahn Ji-Young
Park Mi-Youn
Abstract
Background: Light-based and laser therapy have emerged as alternative therapies for the treatment of acne. Blue and red light-emitting diode (LED) phototherapy and pulsed dye laser (PDL) therapy are recognized as effective modalities in the treatment of acne vulgaris.

Objective: To compare the efficacy of LED phototherapy and PDL therapy in the treatment of acne.

Methods: We randomly allocated a total of 11 patients to receive LED combination therapy or PDL monotherapy.
Outcome assessments included the number of inflammatory and non-inflammatory lesions, investigator¡¯s and subject¡¯s assessment, MexameterTM and CorneometerTM measurements.

Results: Five men and six women were enrolled in the study. After treatment, a greater improvement in the inflammatory and non-inflammatory lesions was recorded in the LED treatment group. Erythema score decreased more in the PDL treatment group than in the LED treatment group. Patient¡¯s self-satisfaction was better in the LED treatment group than in the PDL treatment group.

Conclusion: This study suggests that both combination LED phototherapy and PDL monotherapy could be effective in the treatment of acne. Additional large-scale studies should be conducted to compare the efficacy of these two treatments.
KEYWORD
Acne vulgaris, Low-level light therapy, Phototherapy, Lasers
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